Crisis V

Crisis V, also known as The Infinity War, involved a race of humanity's greatest heroes to defeat a God-like alien from infinity stones created by the ToMonitor and the AnToMonitor.

This war resulted in a few deaths of the heroes, but there were next to none innocent aliens/humans killed.

The War
This war involved the antiparagon of Power and his infinity stones, which ultimately led to the deaths of half of E-1's population.

However, the heroes went back in time to prevent this and eventually succeeded and brought the dead back to life

Known Paragons
Humanity - Tony Stark

Magic - Doctor Strange

Honor - Captain America

(Anti) Power - Thanos